MabSelect™ SuRe 70 protein A resin

Alkaline-stable protein A ligand

As native protein A is sensitive to alkaline conditions, the ligand in MabSelect™ SuRe 70 resin, also used in the MabSelect SuRe™ resin, has been stabilized by engineering one of the IgG-binding domains of protein A. The MabSelect™ SuRe 70 resin is stable when cleaned with 0.1 M NaOH for 200 cycles and approximately 100 cycles using 0.5 M NaOH without performance loss.

Formats

MabSelect™ SuRe 70 resin is available as bulk resin in 25 mL, 200 mL, 1 L, 5 L, and 10 L containers. The resin can be ordered in pre-packed column formats such as HiTrap™ columns (1 and 5 mL), HiScreen™ columns, and on request as production scale ReadyToProcess™ columns. These formats enable use from lab-scale to commercial-scale manufacturing.

Cytiva’s mAb toolbox

Process volumes, number of batches, target molecule, impurity profile, and cleaning protocols influence which chromatography resin will be most cost-efficient and productive in a given application. Cytiva can support you in a discussion about how to set up your process and to make your process more cost efficient. And with every Cytiva resin you choose, you have Cytiva quality, an extensive security of supply program, and expertise to go along with it. Contact us for a productivity discussion.