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Capto™ Butyl-S hydrophobic interaction chromatography resin

Capto™ Butyl-S is the least hydrophobic resin in the Capto™ HIC resin range. It combines high capacity, high flow rate, and low back pressure.

变体 Array 参考编号: 17549701

变体 Array 参考编号: 17549702

¥4,064.00¥7,727.00

货号 规格描述 价格 数量 操作
17549701 包装规格:25mL
Storage solution:20% ethanol
¥4,064.00
17549702 包装规格:100mL
Storage solution:20% ethanol
¥7,727.00
17549723 包装规格:1L
Storage solution:2% BnOH 0.2 M sodium acetate
17549703 包装规格:1L
Storage solution:20% ethanol
17549724 包装规格:5L
Storage solution:2% BnOH 0.2 M sodium acetate
17549704 包装规格:5L
Storage solution:20% ethanol

Capto™ Butyl-S is a hydrophobic interaction chromatography resin designed for the capture and intermediate stages of protein purification. It is the least hydrophobic resin in the range of high-productivity Capto™ HIC resins.

  • High-productivity resin designed for the binding and elution of relatively strong hydrophobic molecules at comparatively low salt concentrations
  • Improved productivity and process economy in downstream operations compared with predecessor Butyl-S Sepharose™ resin
  • Excellent chemical stability
  • The least hydrophobic resin in the range of high-productivity Capto™ HIC resins
  • Low risk of denaturation of relatively strong hydrophobic solutes

Capto™ Butyl-S high-productivity HIC resin

Capto™ Butyl-S is a custom-designed resin developed for large-scale purification of mAbs, mAb variants, and other biomolecules. It is the least hydrophobic resin in the range of high-productivity Capto™ HIC resins.

This resin is designed for the binding and elution of relatively strong hydrophobic molecules at comparatively low salt concentrations. It is particularly useful during the initial stages of a separation process to remove the bulk of impurities without stringent requirements for conditioning of the sample (e.g., adjustment of pH, salt concentration, etc.).

It is a BioProcess™ resin that meets the demands of large-scale biopharmaceutical manufacturers for efficient and cost-effective protein purification. The resin includes validated manufacturing methods, secured supply, and Regulatory Support File (RSF) to assist process validation and submission to regulatory authorities.

Other Capto™ HIC resins

We offer other Capto™ resins for hydrophobic interaction chromatography with different hydrophobicities (Fig 1).

High-flow and high-capacity HIC resins:

High-resolution HIC resins:

See an overview of our HIC resins.

Relative hydrophobic scale of various resins, based on retention of ribonuclease A, lysozyme, and α-Chymotrypsin. Can change with running conditions and proteins. The resins highlighted in bold are the Capto™ HIC resins, which enable optimized productivity compared to Sepharose™ based resins.

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