Pegasus Protect membrane in Kleenpak capsules

Process developers can quickly deliver a robust, scalable virus filtration process using a minimum of sample volume, and be confident of successful virus validation. This choice supports clinical manufacturing with a solution that is easy to use and versatile to work alone or with integrated and automated single-use systems.

Materials of Construction

Filter Membrane: Nylon
Support and Drainage: Polyester
Core and cage: Polypropylene
Capsule hardware: Polyester

Retention Ratings

Pore size : 0.2 μm nominal

Effective Filter Area (EFA) (Nominal)

286 cm2

Operating Parameters

Maximum Temperature: 40°C
Maximum Pressure: 4.1 bar (60 psi)*
Maximum Differential Pressure: 4.1 bar (60 psi)*

Recommended Operating Conditions

35 mbard (0.5 psid) or 2 mL/min water at 20°C*
*when used with Pegasus Prime Mini Kleenpak capsules at 2.1 bard (30 psid)

Steam Autoclaving

Cumulative autoclave time: 16 hours at 125°C*
4 hours at 140°C
* laboratory tests (1-hour cycles). Contact Pall for recommended procedures Warning; Kleenpak capsules must not be steam sterilized in-situ by passing steam through under pressure

Typical Hold-Up Volume (with air purge)

< 125 μL

Dimensions (Nominal)

Length: 11.7 cm (4.6 in.)
Diameter including valves: 9.4 cm (3.7 in.)

Connection Type

1 in. sanitary flange inlet
½ in. sanitary flange outlet

Scalable Solutions

Prefiltration area and flowrate are critical variables that may affect the performance of Pegasus Protect prefiltration and Pegasus Prime virus removal filters when used in combination.

To control these variables Pegasus Protect prefiltration media is available in a range of formats, designed to maintain a consistent pre-filter to virus-filter ratio. This control ensures predictable and consistent performance at all scales from the initial Microdisc scale trials to clinical manufacturing.